Publications

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Intellectual property

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1. Chenyu Gao, Bennett A. Landman, Michael E. Kim. 2024. System and Method of Brain Age Identification for Predicting Neuro-Degenerative Disease. U.S. Patent 63/701,861, filed Oct 1, 2024. Provisional patent.

First-authored Manuscripts Under Review

1. Chenyu Gao*, Kaiwen Xu*, Michael E. Kim, Lianrui Zuo, Zhiyuan Li, Derek B. Archer, Timothy J. Hohman, Ann Zenobia Moore, Luigi Ferrucci, Lori L. Beason-Held, Susan M. Resnick, Christos Davatzikos, Jerry L. Prince, Bennett A. Landman. “Pitfalls of defacing whole-head MRI: re-identification risk with diffusion models and compromised research potential”. arXiv

Refereed Journal Articles

1. Chenyu Gao, Michael E. Kim, Karthik Ramadass, Praitayini Kanakaraj, Aravind R. Krishnan, Adam M. Saunders, Nancy R. Newlin, Ho Hin Lee, Qi Yang, Warren D. Taylor, Brian D. Boyd, Lori L. Beason-Held, Susan M. Resnick, Lisa L. Barnes, David A. Bennett, Katherine D. Van Schaik, Derek B. Archer, Timothy J. Hohman, Angela L. Jefferson, Ivana Išgum, Daniel Moyer, Yuankai Huo, Kurt G. Schilling, Lianrui Zuo, Shunxing Bao, Nazirah Mohd Khairi, Zhiyuan Li, Christos Davatzikos, Bennett A. Landman. “Brain age identification from diffusion MRI synergistically predicts neurodegenerative disease”. Imaging Neuroscience. 2025. (accepted on March 25, 2025)
2. Chenyu Gao, Shunxing Bao, Michael E Kim, Nancy R Newlin, Praitayini Kanakaraj, Tianyuan Yao, Gaurav Rudravaram, Yuankai Huo, Daniel Moyer, Kurt Schilling, Walter A Kukull, Arthur W Toga, Derek B Archer, Timothy J Hohman, Bennett A Landman, Zhiyuan Li. “Field-of-view extension for brain diffusion MRI via deep generative models”. Journal of Medical Imaging. 2024. DOI
3. Chenyu Gao, Qi Yang, Michael E Kim, Nazirah Mohd Khairi, Leon Y Cai, Nancy R Newlin, Praitayini Kanakaraj, Lucas W Remedios, Aravind R Krishnan, Xin Yu, Tianyuan Yao, Panpan Zhang, Kurt G Schilling, Daniel Moyer, Derek B Archer, Susan M Resnick, Bennett A Landman, for the Alzheimer’s Disease Neuroimaging Initiative, the BIOCARD Study team. “Characterizing patterns of diffusion tensor imaging variance in aging brains”. Journal of Medical Imaging. 2024. DOI
4. Chenyu Gao, Bennett A. Landman, Jerry L. Prince, Aaron Carass. “Reproducibility evaluation of the effects of MRI defacing on brain segmentation”. Journal of Medical Imaging. 2023. DOI
5. Michael E Kim, Chenyu Gao, Leon Y Cai, Qi Yang, Nancy R Newlin, Karthik Ramadass, Angela Jefferson, Derek Archer, Niranjana Shashikumar, Kimberly R Pechman, Katherine A Gifford, Timothy J Hohman, Lori L Beason-Held, Susan M Resnick, Stefan Winzeck, Kurt G Schilling, Panpan Zhang, Daniel Moyer, Bennett A Landman. “Empirical assessment of the assumptions of ComBat with diffusion tensor imaging”. Journal of Medical Imaging. 2024. DOI
6. Kurt G Schilling, Karthik Ramadass, Viljami Sairanen, Michael E Kim, Francois Rheault, Nancy Newlin, Tin Nguyen, Laura Barquero, Micah D’archangel, Chenyu Gao, Ema Topolnjak, Nazirah Mohd Khairi, Derek Archer, Lori L Beason‐Held, Susan M Resnick, Timothy Hohman, Laurie Cutting, Julie Schneider, Lisa L Barnes, David A Bennett, Konstantinos Arfanakis, Sophia Vinci‐Booher, Marilyn Albert, BIOCARD Study Team, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Aging Brain: Vasculature, Ischemia, and Behavior (ABVIB), Daniel Moyer, Bennett A Landman. “Head Motion in Diffusion Magnetic Resonance Imaging: Quantification, Mitigation, and Structural Associations in Large, Cross‐Sectional Datasets Across the Lifespan”. Human Brain Mapping. 2025. DOI
7. Adam M Saunders, Michael E Kim, Chenyu Gao, Lucas W Remedios, Aravind R Krishnan, Kurt G Schilling, Kristin P O’Grady, Seth A Smith, Bennett A Landman. “Comparison and calibration of MP2RAGE quantitative T1 values to multi-TI inversion recovery T1 values”. Magnetic Resonance Imaging. 2025. DOI
8. Amalia Peterson, Aditi Sathe, Dimitrios Zaras, Yisu Yang, Alaina Durant, Kacie D Deters, Niranjana Shashikumar, Kimberly R Pechman, Michael E Kim, Chenyu Gao, Nazirah Mohd Khairi, Zhiyuan Li, Tianyuan Yao, Yuankai Huo, Logan Dumitrescu, Katherine A Gifford, Jo Ellen Wilson, Francis E Cambronero, Shannon L Risacher, Lori L Beason-Held, Yang An, Konstantinos Arfanakis, Guray Erus, Christos Davatzikos, Duygu Tosun, Arthur W Toga, Paul M Thompson, Elizabeth C Mormino, Mohamad Habes, Di Wang, Panpan Zhang, Kurt Schilling, Marilyn Albert, Walter Kukull, Sarah A Biber, Bennett A Landman, Sterling C Johnson, Julie Schneider, Lisa L Barnes, David A Bennett, Angela L Jefferson, Susan M Resnick, Andrew J Saykin, Timothy J Hohman, Derek B Archer, Alzheimer’s Disease Neuroimaging Initiative (ADNI), BIOCARD Study Team. “Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer’s disease”. Alzheimer’s & dementia. 2024. DOI
9. Praitayini Kanakaraj, Tianyuan Yao, Leon Y Cai, Ho Hin Lee, Nancy R Newlin, Michael E Kim, Chenyu Gao, Kimberly R Pechman, Derek Archer, Timothy Hohman, Angela Jefferson, Lori L Beason-Held, Susan M Resnick, Alzheimer’s Disease Neuroimaging Initiative (ADNI), BIOCARD Study Team, Eleftherios Garyfallidis, Adam Anderson, Kurt G Schilling, Bennett A Landman, Daniel Moyer. “DeepN4: Learning N4ITK Bias Field Correction for T1-weighted Images”. Neuroinformatics. 2024. DOI
10. Lili Wang, Long Chen, Jiping Wang, Liying Wang, Chenyu Gao, Bo Li, Yuanzheng Wang, Jun Wu, Changyun Quan. “Bioactive gelatin cryogels with BMP‐2 biomimetic peptide and VEGF: a potential scaffold for synergistically induced osteogenesis”. Chinese Chemical Letters. 2022. DOI
11. Mengen Zhao, Chao Zhang, Chenyu Gao, Zhaoying Wu. “Alendronate-decorated strontium-containing bioactive glass nanoparticles with dual osteogenic and anti-osteoclastic effects for osteoporosis”. Journal of Non-Crystalline Solids. 2023. DOI

Refereed Conference Papers

1. Chenyu Gao, Michael E Kim, Ho Hin Lee, Qi Yang, Nazirah Mohd Khairi, Praitayini Kanakaraj, Nancy R Newlin, Derek B Archer, Angela L Jefferson, Warren D Taylor, Brian D Boyd, Lori L Beason-Held, Susan M Resnick, Yuankai Huo, Katherine D Van Schaik, Kurt G Schilling, Daniel Moyer, Ivana Išgum, Bennett A Landman. “Predicting age from white matter diffusivity with residual learning”. Medical Imaging 2024: Image Processing. International Society for Optics and Photonics (SPIE). 2024. DOI
2. Chenyu Gao, Linghao Jin, Jerry L Prince, Aaron Carass. “Effects of defacing whole head MRI on neuroanalysis”. Medical Imaging 2022: Image Processing. International Society for Optics and Photonics (SPIE). 2022. DOI
3. Ema Topolnjak*, Chenyu Gao*, Lori L Beason-Held, Susan M Resnick, Kurt G Schilling, Bennett A Landman. “Assessment of subject head motion in diffusion MRI”. Medical Imaging 2024: Image Processing. International Society for Optics and Photonics (SPIE). 2024. DOI
4. Aravind R Krishnan, Kaiwen Xu, Thomas Li, Chenyu Gao, Lucas W Remedios, Praitayini Kanakaraj, Ho Hin Lee, Shunxing Bao, Kim L Sandler, Fabien Maldonado, Ivana Išgum, Bennett A Landman. “Inter-vendor harmonization of CT reconstruction kernels using unpaired image translation”. Medical Imaging 2024: Image Processing. International Society for Optics and Photonics (SPIE). 2024. DOI
5. Michael E Kim, Ho Hin Lee, Karthik Ramadass, Chenyu Gao, Katherine Van Schaik, Eric Tkaczyk, Jeffrey Spraggins, Daniel C Moyer, Bennett A Landman. “Characterizing low-cost registration for photographic images to computed tomography”. Medical Imaging 2024: Clinical and Biomedical Imaging. International Society for Optics and Photonics (SPIE). 2024. DOI
6. Hanliang Xu, Nancy R Newlin, Michael E Kim, Chenyu Gao, Praitayini Kanakaraj, Aravind R Krishnan, Lucas W Remedios, Nazirah Mohd Khairi, Kimberly Pechman, Derek Archer, Timothy J Hohman, Angela L Jefferson, Ivana Isgum, Yuankai Huo, Daniel Moyer, Kurt G Schilling, Bennett A Landman, BIOCARD Study Team. “Evaluation of mean shift, ComBat, and CycleGAN for harmonizing brain connectivity matrices across sites”. Medical Imaging 2024: Image Processing. International Society for Optics and Photonics (SPIE). 2024. DOI
7. Tian Yu, Yunhe Li, Michael E Kim, Chenyu Gao, Qi Yang, Leon Y Cai, Susane M Resnick, Lori L Beason-Held, Daniel C Moyer, Kurt G Schilling, Bennett A Landman. “Tractography with T1-weighted MRI and associated anatomical constraints on clinical quality diffusion MRI”. Medical Imaging 2024: Image Processing. International Society for Optics and Photonics (SPIE). 2024. DOI

Preprints

1. Michael E Kim, Chenyu Gao, Karthik Ramadass, Praitayini Kanakaraj, Nancy R Newlin, Gaurav Rudravaram, Kurt G Schilling, Blake E Dewey, David A Bennett, Sid OBryant, Robert C Barber, Derek Archer, Timothy J Hohman, Shunxing Bao, Zhiyuan Li, Bennett A Landman, Nazirah Mohd Khairi, The Alzheimers Disease Neuroimaging Initiative, The HABSHD Study Team. “Scalable quality control on processing of large diffusion-weighted and structural magnetic resonance imaging datasets”. 2024. arXiv
2. Zhiyuan Li, Tianyuan Yao, Praitayini Kanakaraj, Chenyu Gao, Shunxing Bao, Lianrui Zuo, Michael E Kim, Nancy R Newlin, Gaurav Rudravaram, Nazirah M Khairi, Yuankai Huo, Kurt G Schilling, Walter A Kukull, Arthur W Toga, Derek B Archer, Timothy J Hohman, Bennett A Landman. “Multi-Modality Conditioned Variational U-Net for Field-of-View Extension in Brain Diffusion MRI”. 2024. arXiv
3. Michael E Kim, Karthik Ramadass, Chenyu Gao, Praitayini Kanakaraj, Nancy R Newlin, Gaurav Rudravaram, Kurt G Schilling, Blake E Dewey, Derek Archer, Timothy J Hohman, Zhiyuan Li, Shunxing Bao, Bennett A Landman, Nazirah Mohd Khairi. “Scalable, reproducible, and cost-effective processing of large-scale medical imaging datasets”. 2024. arXiv
4. Joshua T. Vogelstein, Jayanta Dey, Hayden S. Helm, Will LeVine, Ronak D. Mehta, Tyler M. Tomita, Haoyin Xu, Ali Geisa, Qingyang Wang, Gido M. van de Ven, Chenyu Gao, Weiwei Yang, Bryan Tower, Jonathan Larson, Christopher M. White, Carey E. Priebe. “A Simple Lifelong Learning Approach”. 2020. arXiv