Bone is well known for its self-healing abilities. However, for large-scale defects, bone cannot heal itself completely. In such case, external intervention is needed. By implanting a bioactive scaffold into the defect area, we provide a place for cells to adhere, proliferate and differentiate, thus accelerating the process of bone tissue regeneration.
Schematic illustration of bioactive gelatin cryogels with BMP-2 biomimetic peptide and VEGF for synergistically induced osteogenesis.
The paper has been accepted by Chinese Chemical Letters.